SA Asks: What’s the most attractive nuclear energy stock right now?

Nuclear energy has moved from the sidelines back into the spotlight, driven in part by the increasing demand for electricity from AI data centers. To better understand the investment landscape in this sector, we asked Seeking Alpha analysts Julia Ostian and Jack Bowman which stocks they consider to be the most promising.

**Quick Insights**

Currently, NuScale Power (SMR) leads the pack thanks to having approval from the U.S. Nuclear Regulatory Commission (NRC) and generating revenue from early-stage projects. This regulatory endorsement positions NuScale as a frontrunner in the small modular reactor (SMR) space.

However, these stocks are highly volatile. For example, Oklo (OKLO) faces significant risks prior to regulatory approval. Investors should be cautious due to concerns such as heavy insider selling, lengthy development timelines, and broader uncertainties impacting the nuclear energy industry as a whole.

Energy Fuels (UUUU) is another notable player. The company stands to benefit as demand for uranium and rare earth elements rises alongside nuclear energy adoption. Supply constraints and geopolitical tensions further enhance its growth prospects.

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More Trending News

**Related Stocks**
| Symbol | Last Price | % Change |
| —— | ———- | ——– |
| UUUU | — | — |
| SMR | — | — |
| OKLO | — | — |

Stay updated with trending analyses and the latest news on these stocks to make informed investment decisions in the evolving nuclear energy sector.
https://seekingalpha.com/news/4505439-sa-asks-whats-the-most-attractive-nuclear-energy-stock-right-now?utm_source=feed_news_all&utm_medium=referral&feed_item_type=news

حاسبة اليوم: كم عدد الأشهر بين الأوقات؟

دعامات المشاهير الذين لديهم مصادر داخل حالة تيبيراري

مطعم تاي تونغ تحدث عن الأكل الصيني داخل سياتل لتجربته الآن!
تُعَد تجربة الطعام في مطعم تاي تونغ فرصة مميزة للاستمتاع بألذ المأكولات الصينية في سياتل. بدءًا من النكهات الغنية وحتى الأطباق المجهزة بعناية، يتيح المطعم تجربة طعام لا تُنسى ترضي كافة الأذواق.

تنشيط أنسجة MAIT بـ TCR ودور السيتوكينات

تُعد المواد الطافية مهمة بعيدًا عن أنسجة MAIT المنشَّطة بواسطة TCR. تهدف الدراسات الحديثة إلى توصيف الاستجابة المستقلة لـ TCR داخل المختبر. تُظهر أنسجة MAIT حركيات مختلفة عند التنشيط بوساطة السيتوكينات، مما يسبب عددًا من الحلول الوظيفية.

يصل التنشيط بواسطة السيتوكينات إلى ذروته بعد 20 يومًا تقريبًا، بينما تحاول إشارة TCR تقليل التنشيط إلى أعلى مستوى متكرر ست مرات. تلعب إشارات IL-12 وIL-18 دورًا محوريًا في تنظيم إنتاج IFN-γ، الذي يُعد عاملًا رئيسيًا في الاستجابة المناعية. يُعتبر التنشيط بواسطة إثارة TCR أكثر تعقيدًا وينتج عنه استجابات متعددة الوظائف.

معلومات جغرافية عن تيبيراري

تيبيراري هي منطقة جغرافية تقع في مقاطعة بعيدة عن مونستر، جنوب وسط أيرلندا، وتمتد بين قناتي شانون وسوير. تعتبر أكبر منطقة داخلية في البلاد، وتتميز بمناظر طبيعية خلابة تشمل جبال جالتي وبحيرة سوير الجديدة.

توفر المقاطعة خرائط ومعلومات رحلات شاملة لمساعدتك على تخطيط مغامراتك فيها، مع نصائح إقليمية تساعدك في تحقيق أقصى استفادة من زيارتك.

أهمية إشارات السيتوكين في تنشيط خلايا MAIT

تلعب إنترلوكينات IL-12 وIL-18 دورًا مهمًا في استجابة خلايا MAIT لبعض الكائنات الحية الدقيقة، بما في ذلك Bacillus Calmette-Guérin (BCG).
تعتمد حاجة خلايا MAIT لتنشيطها على إشارات TCR أو السيتوكينات، وتتأثر هذه الحاجة بنوعية المستضد الذي يتم تقديمه.

في الحالات المعدية، مثل الإصابة بـ F. Tularensis، أظهرت الدراسات على الفئران دورًا حيويًا لسيتوكينات MAIT1 في الرئة. كما يظهر مرض Longbeachae استقطاب MAIT17 ويؤدي إلى زيادة استجابات MAIT1، مما يعكس تعديلًا في سبل استجابة MAIT للعدوى تبعًا لبيئة السيتوكينات.

على الرغم من أن خلايا MAIT البشرية تظهر تمايزًا وظيفيًا كبيرًا، إلا أن استجابتها تتكيف وفقًا لبيئاتها المختلفة وأنظمتها البيئية.

التحليلات الجزيئية لاستجابات MAIT

تشير الدراسات النسخية إلى أن تحفيز TCR والسيتوكينات يثيران برامج جينية معينة داخل أنسجة MAIT، مما يؤدي إلى استجابات مناعية مميزة.
بعض العوامل التنظيمية، مثل STAT1 وIKZF1، تلعب دورًا في التنشيط بواسطة السيتوكينات. كما أن توليفة التنشيط بين TCR والسيتوكينات قد تؤدي إلى إنتاج IL-17، مما يعكس تعاونًا جديدًا بين هذه المسارات.

دور نوع الإنترفيرون في تحفيز MAIT

ينشط نوع الإنترفيرون (IFN-α وIFN-β) خلايا MAIT بشكل فعال. أظهرت الدراسات أن الإنترفيرون من النوع الأول قادر على تحفيز الاستجابات السامة للخلايا بالإضافة إلى تحسين إفراز السيتوكينات عند التنشيط بواسطة TCR.

يلعب IFN-α دورًا تمهيديًا هامًا يعزز استجابة MAIT عند التفاعل مع مستقبلات مثل TLR7 وTLR8، مما يزيد من كفاءة الاستجابة المناعية.

اللدونة الوظيفية لأنسجة MAIT ودورها في التوازن المناعي

تتميز خلايا MAIT بالقدرة على التكيف واللدونة الوظيفية استجابةً للتغيرات في بيئة السيتوكينات الدقيقة. يسمح ذلك لأنسجة MAIT بضبط نشاطها ليكون إما خبيرًا أو مضادًا للالتهابات، حسب سياق الإصابة أو الاستتباب في الأنسجة المختلفة.

معلومات تقنية إضافية

– يُذكَر أن هذه المقالة منشورة برخصة Creative Commons Attribution (CC BY).
– يُسمح بإعادة التوزيع مع ضرورة الاقتباس والإشارة إلى المصدر والكاتب الأصلي حسب الممارسات الأكاديمية المعتمدة.

إذا كنت تبحث عن تجربة طعام صينية مميزة في سياتل، أو ترغب في فهم أعمق للاستجابات المناعية المتعلقة بخلايا MAIT، فإن المعلومات أعلاه تعطيك لمحة شاملة تجمع بين الثقافة والطبيعة والعلوم الحيوية.
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Infisical (YC W23) Is Hiring Full Stack Engineers

**Join Infisical: Building the Open Source Security Infrastructure Stack for the AI Era**

Infisical is on the lookout for exceptional talent to join our teams in building the open source security infrastructure stack tailored for the AI era. We’re crafting a generational company with a world-class engineering team. This isn’t a place to coast — if you want to grow fast, take ownership, and solve tough problems, you’ll be challenged like nowhere else.

### What We’re Looking For

We are searching for an exceptional **Full Stack Engineer** to help build, optimize, and expand the foundation of our platform. Our hiring standards remain exceptionally high because we expect engineers to tackle a broad range of challenges daily.

Past engineering initiatives include:
– Developing strategies for secret rotation and dynamic secrets
– Building a gateway to provide secure access to private resources
– Implementing protocols like EST and KMIP
– Creating integrations for syncing secrets across cloud providers
– Launching new product lines such as Infisical PKI and Infisical SSH

As part of our team, you’ll work closely with our CTO and engineering experts to:
– Develop and maintain features while communicating directly with enterprise customers
– Expand new product lines including Infisical PKI, Infisical SSH, and Infisical KMS
– Experiment with innovative approaches applying AI to secrets management and broader security infrastructure

### Requirements

– Deep technical mastery of the JavaScript ecosystem, particularly **React.js, Node.js, and TypeScript**
– Exceptional attention to detail and a strong eagerness to learn
– A bias toward action — able to make decisions with incomplete information, iterate quickly, and take calculated risks
– Flexible location: You must be based in one of the approved countries and available to collaborate with the team until at least 3pm Eastern Time (EST)

### Bonus Skills

– Expertise in Go
– Understanding of DevOps and developer tools
– Previous founder or startup experience
– Experience building open source projects or developer tools professionally or personally
– Excellent written and oral communication skills to engage directly with customers

### How You’ll Grow

In this role, you’ll play a pivotal part in shaping Infisical’s future by making key technical decisions, establishing foundational processes, and tackling complex scalability challenges. As you gain experience and as our team expands, you’ll have the opportunity to take full ownership of specific platform areas, driving them end-to-end with autonomy and impact.

Overall, you will be one of the defining members of our team as we scale to thousands of customers over the next 18 months.

### Team, Values & Benefits

Our team brings together experience from leading companies like Figma, AWS, and Red Hat. While we operate primarily as a remote team, we maintain a strong presence in San Francisco with an office and come together throughout the year for off-sites, conferences, and team gatherings.

At Infisical, we offer competitive compensation including salary and equity options. The salary range for this role depends on location, experience, and seniority.

Additional benefits include:
– Lunch stipend
– Work setup budget

More details can be found on our [careers page](#).

### About Infisical

Infisical is the open source security infrastructure platform engineers trust for secrets management, internal PKI, key management, and SSH workflow orchestration. Each month, we securely manage over 1.5 billion secrets — including application configurations, database credentials, certificates, and more.

We’ve raised $19 million from Y Combinator, Google, and Elad Gil. Our customers include Hugging Face, Lucid, and LG.

Join us on a mission to make security easier for all developers, starting with secrets management.

Ready to make an impact? Apply now and be part of the future of security infrastructure.
https://www.ycombinator.com/companies/infisical/jobs/0gY2Da1-full-stack-engineer-global

FanDuel Promo Code: Claim $300 Bonus for NFL Week 7 Games

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https://wtop.com/sports/2025/10/fanduel-promo-code-claim-300-bonus-for-nfl-week-7-games/

Penn State blows late lead for fourth straight loss in first game since James Franklin firing

It’s a new era for Penn State football, but it started in the same crushing fashion. In their first game since firing longtime head coach James Franklin, the Nittany Lions coughed up a fourth-quarter lead and lost a 25-24 heartbreaker to Iowa on Saturday night at Kinnick Stadium, marking their fourth straight loss.

Penn State fell to a brutal 3-4 on the season and has dropped its first four games in the Big Ten.

“I think we gave everything we had,” interim head coach Terry Smith said following his first game at the helm. “There was no one that didn’t give great effort. We just have to execute.”

The Nittany Lions held a 24-19 lead with just under five minutes to go, until Hawkeyes quarterback Mark Gronkowski ran for 67 yards to set up Kaden Wetjen for a go-ahead rushing touchdown with 3:54 left on the clock. Iowa failed to convert on the two-point conversion, leaving the door open for a Penn State comeback.

However, the Hawkeyes pressured Penn State’s second-string quarterback, Ethan Grunkmeyer, near midfield and forced a fourth-down incompletion. Gronkowski, who set a new career high with 130 rushing yards while adding two touchdowns, iced the game with a 14-yard rush on third down that allowed Iowa to burn the clock.

After dropping their fourth straight game, Penn State tied the record for most consecutive losses in AP poll history for a team that was ranked within the top two in the first poll of the season, according to ESPN.

The loss was a brutal way to kick off Smith’s term in charge following the shock firing of Franklin after 12 seasons. Penn State is a far cry from the squad that marched to the College Football Playoff just a season ago.

After beating up on inferior competition to open the season, the Nittany Lions completely unraveled in conference play, underscored by back-to-back disasters against UCLA and Northwestern.

The former associate head coach inherited a team in complete freefall — a struggling squad without its starting quarterback, Drew Allar, who suffered a season-ending injury.

All things considered, Smith was relatively pleased with the fight he saw from his team on Saturday night.

“I’m super proud of those guys and the way they played,” he said. “We just have to clean it up so that we can finish games.”

Things don’t get any easier for the Nittany Lions, who, after a bye week, will travel to the Horseshoe to face No. 1-ranked powerhouse Ohio State on November 1.
https://nypost.com/2025/10/19/sports/penn-state-blows-late-lead-against-iowa-after-james-franklin-firing/

Coroner says a 7th person has died from injuries in Mississippi Delta town mass shooting

LELAND, Miss. (AP) — A seventh person has died from injuries sustained in a mass shooting following a high school football homecoming game earlier this month in the Mississippi Delta town of Leland, according to local officials.

Washington County coroner LaQuesha Watkins announced Saturday that her office was informed by the Hinds County coroner’s office on Friday about the death of 25-year-old Ebanee Williams.

In connection with the shooting, which occurred around midnight on October 11, nine people have been arrested. Several of those arrested face capital murder charges. The incident also left more than a dozen individuals injured.

The FBI’s Jackson Field Office has been actively posting pictures of suspects wanted for questioning in relation to the mass shooting.

The shooting took place as people were celebrating homecoming weekend in downtown Leland, shortly after the football game.

Authorities have not disclosed a possible motive for the shooting. However, the FBI indicated that the gunfire appears to have been “sparked by a disagreement among several individuals.”
https://wtop.com/national/2025/10/coroner-says-a-7th-person-has-died-from-injuries-in-mississippi-delta-town-mass-shooting/

Nearly half of U.S. adults aren’t confident they could find a good job, while electricity and grocery costs are major sources of stress, poll says

High prices for groceries, housing, and health care continue to be a major concern for many American households. Rising electricity bills and the cost of gas at the pump are also sources of anxiety, according to a recent survey.

Some 47% of U.S. adults are “not very” or “not at all confident” they could find a good job if they wanted to—a significant increase from 37% when the question was last asked in October 2023. Electricity bills are a “major” source of stress for 36% of U.S. adults, especially at a time when the expected build-out of data centers for artificial intelligence could put additional strain on the power grid.

More than half of respondents said the cost of groceries is a “major” source of financial stress. About 4 in 10 reported that housing and health care costs are serious strains, and roughly one-third expressed high stress about gasoline prices.

### Political Implications: Trump’s Economic Challenges

The survey highlights ongoing economic vulnerabilities for former President Donald Trump, who returned to the White House in January promising to quickly tame the inflation surge that occurred during Democratic President Joe Biden’s term. Despite these claims, Trump’s popularity on economic issues remains low amid tariffs, federal worker layoffs, partisan conflicts, and a government shutdown.

Linda Weavil, 76, a retiree from Greensboro, North Carolina, voted for Trump last year because he “seems like a smart businessman.” However, she expressed concerns about his tariffs, citing increased prices for items like chocolate-covered pecans sold at her church group fundraiser. “I think he’s doing a great job on a lot of things, but I’m afraid our coffee and chocolate prices have gone up because of tariffs,” she said. “That’s a kick in the back of the American people.”

### Approval Ratings and Job Market Outlook

The poll found that 36% of U.S. adults approve of how Trump is handling the economy, a figure that has remained steady this year despite the economic uncertainty caused by tariffs. Among Republicans, 71% feel positive about his economic leadership, though this approval within his own party is relatively low—potentially problematic for upcoming races for governor in New Jersey and Virginia, as well as the 2026 midterm elections.

At a similar point in Biden’s term, an AP-NORC poll conducted in October 2021 found that 41% of U.S. adults approved of how he managed the economy, including about 73% of Democrats. This higher overall approval was largely due to independent voters, with 29% supporting Biden’s economic handling compared with 18% for Trump now.

Hiring was notably stronger during Biden’s presidency as the U.S. recovered from pandemic-related lockdowns. However, job gains have slowed significantly under Trump, averaging less than 27,000 per month after the April tariff announcements. This slowdown is reflected in public confidence: four years ago, 36% of survey respondents were “extremely” or “very” confident in their ability to secure a good job—now, that figure has dropped to 21%.

### Rising Electricity Costs: An Emerging Concern

Electricity costs have become an increasing worry. Trump’s decision to cancel funding for renewable energy projects and to impose tariffs on equipment necessary for factories and power plants has added to the financial burden. These increased costs come before the anticipated surge in electricity demand from new data centers built for artificial intelligence.

While 36% of Americans see electricity bills as a major concern, 40% identify costs as a “minor” stress, and 23% say their utility bills are “not a source” of stress at all.

Kevin Halsey, 58, from Normal, Illinois, shared his experience: his monthly electricity bill used to be $90 during summer months thanks to solar panels but has since soared to $300. A telecommunications worker and Democratic voter, Halsey describes the economy as “crap” and remains pessimistic. “I don’t see this as getting better,” he said.

### Public Skepticism Despite Economic Indicators

Both Trump and Biden face a similar economic dilemma. While indicators such as low unemployment, stock market gains, and steady economic growth suggest a solid economy, the public remains skeptical.

Some 68% of U.S. adults describe the economy as “poor,” with only 32% saying it’s “good,” reflecting a consistent sentiment over the past year. Regarding personal finances, 59% say their family finances are “holding steady,” but only 12% feel they are “getting ahead,” while 28% say they are “falling behind.”

### Economic Strains Across the Board

The widespread sense of economic uncertainty is fueled by multiple factors, signaling that middle-class stability may be increasingly out of reach for many Americans. The vast majority report at least “minor” stress related to groceries, health care, housing, taxes, wages, and gasoline costs.

Nearly half (47%) say they are “not very” or “not at all” confident they could pay an unexpected medical expense, and 52% have low confidence about having enough savings for retirement. Furthermore, 63% lack confidence in their ability to buy a new home.

Confidence in homebuying is especially low among young adults: about 80% of those under age 30 say they are “not very” or “not at all confident” they could purchase a house, compared with roughly 60% of adults aged 60 and older.

### Personal Stories Reflect Economic Reality

For 54% of U.S. adults, the cost of groceries is a major source of stress. Unique Hopkins, 36, from Youngstown, Ohio, now works two jobs after her teenage daughter had a baby. She describes herself as part of the “working poor,” barely able to get by. Hopkins voted for Trump in 2016 but switched allegiance to the Democrats, feeling that Trump’s ego prevented him from uniting the country and solving problems.

“It’s his way or no way,” she said. “Nobody is going to unite with Trump if it’s all about you, you, you.”

This survey underlines the deep economic concerns affecting American households today—ranging from job security and rising living costs to skepticism about political leadership—and highlights the challenges ahead for both parties.
https://fortune.com/2025/10/19/us-job-market-trump-economy-approval-tariffs-electricity-grocery-financial-stress/

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Man killed in multi-vehicle crash in Lakeville

LAKEVILLE, MASS. (WHDH) — Police are investigating a crash in Lakeville that occurred on Saturday night, resulting in the death of a 66-year-old man and leaving two other people hospitalized with non-life-threatening injuries.

Officers responded to a reported crash near 164 County Road around 7 p.m. Upon arrival, they found a two-vehicle collision that took place between Highland Road and Freetown Street, according to Lakeville police.

The 66-year-old man from Lakeville, whose name has not been released, was transported to the hospital where he was pronounced dead. The occupants of the other vehicle were also hospitalized with injuries that are not considered life-threatening.

The investigation into the crash is ongoing. Lakeville Police are being assisted by the Massachusetts State Police Collision Analysis and Reconstruction Section, the State Police Crime Scene Services Section, and State Police detectives assigned to the Plymouth County District Attorney’s Office.
https://whdh.com/news/man-killed-in-multi-vehicle-crash-in-lakeville/

Filming at the Speed of Light, About One Foot per Nanosecond

Brian Haidet recently showcased an incredible experiment on his AlphaPhoenix channel: a laser beam recorded at an astonishing 2 billion frames per second. Well, sort of. The trick? The video itself is only one pixel by one pixel. However, by repeating this tiny video over and over, Brian is able to build up a full rendering that reveals fascinating details about the laser’s motion.

For this project, Brian went back to the drawing board and completely rebuilt his entire apparatus from scratch. Just a few months earlier, in December of last year, he had already created a video camera capable of recording at 1,000,000,000 frames per second. To reach the new milestone of 2,000,000,000 frames per second — and achieve significantly improved resolution — Brian upgraded virtually every component. This included the motors, hardware, oscilloscope, signaling system, recording software, and processing software. Essentially, everything was revamped to push the boundaries of ultra-high-speed imaging.

One of the coolest effects produced by this new setup is how the laser light appears to travel noticeably faster when moving toward the camera than when moving away from it. This is actually an artifact of the experimental setup: laser beams reflecting off fog particles closer to the camera arrive sooner than those bouncing back from particles that are further away.

In other words, what you’re seeing is a real-world visualization of special relativity, all happening in Brian’s garage. It’s an impressive feat and a delightful demonstration of both physics and engineering coming together in a stunning way. Pretty cool!
https://hackaday.com/2025/10/19/filming-at-the-speed-of-light-about-one-foot-per-nanosecond/

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