Surprising benefits and risks of diabetes medicine metformin

Metformin is one of the most widely used medicines for treating type 2 diabetes. This condition occurs when the body struggles to keep blood sugar levels under control. Often, this happens because the body either doesn’t produce enough insulin or doesn’t respond to it properly.

Insulin is a hormone that helps move sugar from the blood into cells, where it’s used for energy. When insulin doesn’t work well, sugar stays in the blood, which can lead to serious health problems over time.

### How Metformin Works

Metformin helps by lowering the amount of sugar made by the liver. It also improves the body’s response to insulin, making it easier for sugar to move into the cells. This keeps blood sugar levels within a healthy range.

But Metformin does more than just control blood sugar—it also protects the heart. People with diabetes are at a higher risk of heart disease, which can lead to heart attacks or strokes. A well-known study published in *The Lancet* showed that people with diabetes who took Metformin had a 39% lower risk of heart problems compared to those who didn’t take it. This means Metformin helps prevent serious health complications, not just diabetes symptoms.

### Additional Benefits of Metformin

Another advantage of Metformin is its role in supporting weight loss. Many people with type 2 diabetes find it difficult to lose weight, and being overweight can worsen diabetes. Metformin helps by lowering appetite and improving how the body uses insulin. This makes it easier to lose weight and maintain better diabetes control.

Metformin also reduces inflammation in the body. Inflammation occurs when the immune system remains active even without a real threat. Long-term inflammation is associated with diseases such as heart disease and cancer. By lowering inflammation, Metformin might offer additional protection against these serious conditions.

### Possible Side Effects

Like all medicines, Metformin can cause side effects. The most common ones affect the stomach. Some people may experience nausea, diarrhea, stomach pain, or vomiting. These symptoms are usually mild and often improve when the medicine is taken with food.

One side effect that doctors monitor is low levels of vitamin B12. Metformin can reduce the body’s ability to absorb this vitamin, which is essential for healthy nerves and blood. If vitamin B12 levels get too low, a person might feel very tired or develop nerve problems. Therefore, doctors sometimes check B12 levels in people taking Metformin long-term.

A rare but serious side effect of Metformin is lactic acidosis. This condition occurs when too much lactic acid builds up in the body and can be life-threatening. It is more likely to happen in people with kidney or liver problems or those taking very high doses of Metformin. That’s why doctors regularly check kidney function before and during treatment.

Metformin can sometimes cause low blood sugar (hypoglycemia), especially if taken alongside other diabetes medicines or if meals are skipped. Symptoms include shaking, sweating, dizziness, or confusion. If this happens, eating or drinking something sugary and consulting a doctor promptly is important.

### Importance of Regular Medical Check-Ups

Because of these risks, regular visits to a healthcare provider are essential while taking Metformin. Doctors can ensure the medicine is working effectively and check for any complications.

### Conclusion

In conclusion, Metformin is a trusted and effective medicine for people with type 2 diabetes. It lowers blood sugar, protects the heart, supports weight loss, and may help prevent other serious health issues. With regular medical monitoring and proper use, Metformin can help people live longer, healthier lives.

If you are interested in learning more about diabetes, consider reading the following studies:

– *Scientists Find a Promising Treatment for Type 2 Diabetes*
– *Certain Type 2 Diabetes Treatments May Bring Heart Risks*
– *New Type 2 Diabetes Treatment Could Help Patients Stop Taking Insulin*
– *Scientists Find True Cause of Inflammation in Type 2 Diabetes*

These resources provide valuable insights into the latest advancements and considerations in diabetes care.
https://knowridge.com/2025/11/surprising-benefits-and-risks-of-diabetes-medicine-metformin/

Liverpool vs Real Madrid Prediction and Betting Tips | November 4 2025

Liverpool Lock Horns with Real Madrid in Blockbuster Champions League Clash

Liverpool will face Real Madrid in a high-stakes UEFA Champions League matchday four showdown on Tuesday. Both sides have showcased strong form, each securing at least two wins from their opening three group games.

### Recent Form and Performance

Arne Slot’s Liverpool ended a troubling run of two consecutive defeats—and six losses in seven matches across all competitions—with an impressive 2-0 home victory over Aston Villa at the weekend. Goals from Mohamed Salah and Ryan Gravenberch helped the Reds climb to third place in the Premier League standings after 10 games, seven points behind leaders Arsenal, who have 25 points.

In Europe, Liverpool bounced back from a 1-0 defeat at Galatasaray in matchday two with a dominant 5-1 away win over Eintracht Frankfurt. They also started their campaign strongly with a 3-1 home victory against Atletico Madrid. Currently, the Reds sit 10th in their group with six points from three games.

Meanwhile, Xabi Alonso’s Real Madrid head into the clash fresh off a commanding 4-0 home win against Valencia. Kylian Mbappe scored twice, alongside strikes from Jude Bellingham and Alvaro Carreras, extending Los Blancos’ lead at the top of La Liga after 11 matches.

In the Champions League, Real Madrid have been in stellar form, becoming one of five teams to win their first three group-stage games, with a 1-0 victory over Juventus in matchday three. The Spaniards are fifth in the group standings.

### Head-to-Head Stats and Key Numbers

In 12 Champions League meetings, Real Madrid lead Liverpool 7-4, though they lost their most recent encounter 2-0 away at Anfield in November 2024. Madrid have won two of their last four visits to Anfield but also suffered that noted defeat. Liverpool have claimed victory in three of their last five competitive home games, losing twice. Real Madrid have won four of their last five road matches, with only one loss.

**Recent Form (last five matches across all competitions):**
– Liverpool: Win, Loss, Loss, Win, Loss
– Real Madrid: Win, Win, Win, Win, Win

### Match Prediction

While Liverpool has experienced inconsistency after a promising start to the season, Real Madrid are enjoying a sustained run of excellent results, currently unbeaten in their last six matches across all competitions. Although Madrid holds a convincing edge in their head-to-head record, the Reds will be eager to avenge their last home loss to the Spanish giants.

Given Real Madrid’s current form and overall advantage, they are favored to edge out a narrow victory in this clash at Anfield.

**Prediction:** Liverpool 0-1 Real Madrid

### Betting Tips

– Tip 1: Real Madrid to win
– Tip 2: Both teams to score – No (In three of their last four meetings, both teams did not score)
– Tip 3: Under 1.5 goals

Stay tuned for what promises to be an exciting and intense Champions League encounter between two European powerhouses.
https://www.sportskeeda.com/football/liverpool-vs-real-madrid-prediction-betting-tips-november-4-2025

Roundtable: Antisemitism From Within

Message from Jim Robinson:

Dear FRiends,

We need your continuing support to keep FR funded. Your donations are our sole source of funding. No sugar daddies, no advertisers, no paid memberships, no commercial sales, no gimmicks, no tax subsidies. No spam, no pop-ups, no ad trackers.

If you enjoy using FR and agree it’s a worthwhile endeavor, please consider making a contribution today:

Thank you very much and God bless you,

Jim

https://freerepublic.com/focus/f-news/4350191/posts

On the safe side Crossword Clue

We have the 4-letter answer for the crossword clue “On the safe side,” which was last seen in the Seattle Times New Crossword on November 2, 2025. If you’ve been stuck on this clue, we’re here to help you solve it and complete your puzzle with ease.

**On the Safe Side Crossword Clue – Q&A**

**When was the clue “On the safe side” used most recently?**
This clue was last featured in the Seattle Times New Crossword puzzle dated November 2, 2025.

**What is the most recent answer for the “On the safe side” crossword clue?**
The most recent answer for this clue is a 4-letter word: **ALEE**.

**What is the 4-letter answer for “On the safe side”?**
The answer is **ALEE**.

If you encounter this clue in your crossword puzzles, remember that “ALEE” refers to the side sheltered from the wind — essentially, being “on the safe side.” Bookmark this page for quick reference to help you finish your puzzle smoothly!
https://tryhardguides.com/on-the-safe-side-crossword-clue/

Arca’s Jeff Dorman Slams Coinbase CEO for Prediction Market Stunt on Earnings Call

Arca’s Jeff Dorman has openly criticized Coinbase CEO Brian Armstrong for referencing prediction market bets during the company’s recent earnings call.

Dorman expressed his disapproval of Armstrong’s approach, describing the mention of prediction markets as a stunt rather than a substantive part of the financial discussion.

This exchange highlights ongoing tensions in the crypto industry regarding communication strategies and the use of unconventional metrics during official company briefings.

The post Arca’s Jeff Dorman Slams Coinbase CEO for Prediction Market Stunt on Earnings Call appeared first on Cryptonews.
https://cryptonews.com/news/arcas-jeff-dorman-slams-coinbase-ceo-for-prediction-market-stunt-on-earnings-call/

LA Times Crossword November 2 2025 Answers (11/2/25)

Our LA Times Crossword November 2, 2025 Answers Guide

If you’ve found yourself stuck on a clue in today’s LA Times Crossword, our answers guide is here to help you finish the puzzle with ease. The LA Times Crossword is a daily crossword published in the Los Angeles Times, one of the largest newspapers in the United States. Renowned for its challenging clues and clever themes, this puzzle is a favorite among crossword enthusiasts.

**About the LA Times Crossword**

The LA Times Crossword features a traditional-style grid of black and white squares, with clues given in both across and down directions. It offers a daily challenge suited for solvers at all levels, from beginners to experts. Since its introduction in 2005, it has become a beloved tradition for many crossword fans.

Created by a skilled team of crossword constructors, the puzzle incorporates a diverse range of topics. These range from pop culture and current events to science and history. Its themed sections often add an extra layer of complexity, making the solving experience even more engaging.

**LA Times Crossword – November 2, 2025 Answers**

Below, you’ll find the complete list of clues from the November 2, 2025 puzzle, along with their answers. We’ve organized the clues by across and down to help you quickly locate the ones you need. This approach allows you to look up just a few answers without spoiling the rest of the puzzle you may still be solving.

### Across

– 1A Comforting touches
– 5A Perceived
– 9A Puck’s flagship restaurant
– 14A Wound remnant
– 18A 2-Down’s love interest
– 19A Long skirt
– 20A Classic quilted handbag maker
– 21A Goddess of marriage
– 22A Dance of the moonlighters?
– 25A Garden spot
– 26A Many a first-time voter
– 27A Night, in the Eternal City
– 28A Blow up, in a way
– 29A Wiser companion?
– 30A Terra firma
– 35A Tear
– 37A Upper limb
– 39A Blessed event?
– 55A Troubled
– 59A Prefix with -pathic
– 63A Work unit
– 67A Concern
– 76A Flag
– 81A Mathematician Lovelace
– 82A Spotless
– 85A Israeli airline
– 86A Give kudos at a poetry slam
– 89A Tolkien’s Shepherds of the Trees
– 92A Surrounded by
– 95A Tennis icon Arthur
– 96A King or queen
– 101A Principles
– 104A Musician and peace activist Yoko
– 105A Once __ while
– 117A Not moving
– 126A Put in stitches
– 129A Natural balm
– 130A Tantalizing
– 133A Longings

### Down

– 1D Sauce made with basil and pine nuts
– 5D Arrogant
– 7D Over-the-top
– 9D Closes
– 11D Radio receiver
– 12D Take shape
– 15D Surrendered
– 24D Evasive maneuver
– 28D Toon devil
– 31D Catch
– 34D “L’Absinthe” painter
– 41D Prefix with -polis
– 44D Predicaments
– 45D “Evita” name
– 50D Slight advantage
– 54D Jamaican genre
– 56D Gleam
– 60D Not remote
– 65D Rolls-__
– 66D Precursor to overtime
– 68D Some military figs.
– 73D “Ur so funny!”
– 74D Kerfuffles
– 75D Trail
– 78D Facts, for short
– 79D Abel’s brother
– 80D Chipper
– 83D “Se __ español”
– 84D Devoured
– 90D E’en if
– 93D King or queen
– 97D Holds back
– 99D Curry favor with
– 100D Not quite (there)
– 102D Court fig.
– 103D Ointments
– 107D Silly
– 109D Michelangelo masterpiece
– 111D __ acid
– 114D Cunning
– 115D “Citizen Kane” director Welles
– 116D Heads of France
– 124D Whopper
– 125D “Why Can’t We Be Friends?” band

The grid for the puzzle just went live, and we are in the process of publishing all the answers. If you don’t yet see the clue you need, check back shortly!

**Looking for More LA Times Crossword Answers?**

If you’re interested in solutions to other LA Times Crossword puzzles, feel free to browse our [archive of LA Times Crossword Answers](#). We continually update our database to assist you with puzzles from every day.

Enjoy solving, and happy puzzling!
https://tryhardguides.com/la-times-crossword-november-2-2025-answers/

Today in History: November 2, Howard Hughes takes ‘Spruce Goose’ on its only flight

**How to Place an Obituary with Pioneer Press**

To place an obituary, please send an email including the necessary information (detailed below) to **obits@pioneerpress.com**. At this time, there is no option to submit obituaries through our website.

If you have any questions, feel free to contact our obituary desk at **651-228-5263**.

### General Information Required
– Your full name
– Address (City, State, Zip Code)
– Phone number
– Alternate phone number (if any)

### Obituary Specifications
– Name of the deceased
– Obituary text
– A photo file (JPEG or PDF preferred; TIF and other formats accepted). We will contact you if there are any issues with the photo.
– Ad run dates

*Note:* There is a discount for running the obituary more than one day, but this must be scheduled at the time of the first run. If a photo is included, it must be used on all days to qualify for the discount. Please contact us for more information.

### Policies

#### Verification of Death
To publish obituaries, the name and phone number of the funeral home or cremation society handling the arrangements is required. We must contact them during business hours to verify the death.

– If the deceased’s body was donated to the University of Minnesota Anatomy Bequest Program or a similar program, their contact number is required for verification.
– Please allow extra time for contact, especially during limited weekend hours.
– A death certificate is also acceptable for verification (only one of these two options is necessary).

#### Guestbook and Outside Websites
We do **not** allow references to other media sources with guestbooks or obituaries placed elsewhere when submitting notices for print and online. Instead, we may include a funeral home website or family email contact. Please contact us if you have questions about this.

### Obituary Process
Once your submission is complete, we will fax or email you a proof prior to newspaper publication. The proof will include pricing and scheduled publication dates.

– Please review the proof carefully.
– Notify us of any errors or changes **before** the obituary appears, adhering to daily deadlines.
– We are not responsible for errors after the final proofing or post-publication corrections.

For changes to an online obituary after publication, please contact the obituary desk.

### Payment Procedure
Pre-payment is required before publication and must be made by the specified deadline.

– After you receive and approve the proof, call **651-228-5263** to provide your payment details.
– Payments accepted by phone only due to PCI (Payment Card Industry) regulations.

**Payment methods include:**
– Credit card (by phone only)
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### Rates
– Minimum charge: $162 for up to 12 lines.
– Each additional line (beyond 12 lines) is $12 per line.
– Obituaries over 40 lines receive a 7.5% discount per line.
– Second run date: 20% discount on both placements.
– Place three obituaries, and the third placement is free of charge.
– Each photo published is $125 per day. For example, 2 photos run for 2 days equals 4 photo charges totaling $500.

### Deadlines
Please adhere strictly to deadline times to ensure publication on your requested day.

**Hours:** Monday – Friday, 8:00 AM – 5:00 PM (Closed weekends and holidays).

### Memoriam (Non-Obituary) Requests
Memoriam submissions are remembrances of loved ones and are priced differently than obituaries.

For more information regarding memoriam ads, please call **651-228-5280** or email us.

Thank you for choosing Pioneer Press to honor your loved one’s memory.
https://www.twincities.com/2025/11/02/today-in-history-november-2-howard-hughes-takes-spruce-goose-on-its-only-flight/

Tulsa King season 3 episode 7 ending explained: What happens to Jeremiah?

**Tulsa King Season 3 Episode 7 Recap: “Art of War”**

*Premiere Date: November 2, 2025*

The saga of Dwight “The General” Manfredi continues in *Tulsa King* Season 3, Episode 7, titled *Art of War*. This episode escalates the tension as Dwight maneuvers through an increasingly dangerous and complex world filled with shifting allegiances and mounting conflicts.

### Spoiler Alert

*The following article contains spoilers from Tulsa King Season 3, Episode 7. Reader discretion is advised.*

### Episode Overview

Picking up after the fallout from Dwight’s earlier actions, *Art of War* places him face-to-face with multiple new hurdles. His relationships with allies are strained, and he must deal with a desperate confrontation involving the law.

One of the episode’s most shocking moments is the jailing of Jeremiah Dunmire, which marks a dramatic turning point. This raises a compelling question for fans: Is this the end of Jeremiah’s reign, or could he make a comeback in future episodes?

### Jeremiah Dunmire’s Power Collapses

The final moments of Episode 7 are explosive, witnessing the collapse of Jeremiah Dunmire’s once-formidable power. Dwight’s cunning manipulation of key players—Attorney General Sackrider and Governor Thresher—sets the stage for this dramatic shift.

At the height of tension, Jeremiah suffers a devastating betrayal from his closest allies, losing control irreversibly. The climax begins when an enraged Jeremiah storms into Sackrider’s office after Sackrider unexpectedly switches sides. In a fit of rage, Jeremiah attempts to choke Sackrider but is quickly subdued and arrested by security.

The season ends on this cliffhanger, sparking speculation about the future of Jeremiah’s character and what this power vacuum means for Tulsa’s underworld.

### Dwight’s Strategic Maneuvering

After a failed meeting with Ray and the chaos surrounding Montague Distilleries, Dwight is left reeling. Episode 7 captures Dwight’s reflective mindset as he contemplates the battles ahead. Despite enemies closing in from all sides and the apparent crumbling of his empire, Dwight shifts his focus to strategy and the long game instead of panic.

To reclaim power, Dwight forges new alliances and carefully navigates the complex landscape of power plays. One key move is his tentative reconciliation with Ray, who had previously shunned him. Dwight offers Ray access to Montague’s Northeast operations in exchange for a share of the profits, turning tension into opportunity—even if compromise is required.

Despite the shifting power dynamics, Dwight remains confident that he is still in control.

### Dwight’s Encounter with Attorney General Sackrider

A pivotal subplot in this episode is Dwight’s calculated move to influence Attorney General Sackrider, who has been instrumental in restricting Montague Distilleries. Exploiting Sackrider’s personal vulnerabilities—including marriage troubles exacerbated by a gambling addiction—Dwight sends his associate Margaret to gather intel.

Armed with this information, Dwight arranges a meeting with Sackrider at the Bred-2-Buck Casino. During the meeting, Dwight subtly manipulates Sackrider’s luck with loaded dice, driving him into significant debt. Dwight then offers to forgive this debt—on the condition that Sackrider switches allegiances and works for him instead of Jeremiah.

This encounter highlights Dwight’s rising influence and shrewd diplomacy in the ongoing power struggle.

### The Tension Between Jeremiah and Cole

Episode 7 also delves into the strained father-son relationship between Jeremiah and Cole. As Jeremiah’s empire collapses, his anger and desire to maintain control grow more volatile. Conversely, Cole grows increasingly distant, recognizing the futility of following a man who is losing grip over his domain.

Their tense dynamic adds emotional depth to the episode, emphasizing the personal stakes of this criminal war. It also hints at a possible turning point for Cole—breaking free from his father’s toxic influence and carving out his own path.

### The Fall of Jeremiah

The episode’s climax sees Dwight’s strategy come to fruition. After securing Sackrider’s support, Dwight directly confronts Jeremiah at Sackrider’s office. Jeremiah’s pride and arrogance, once his strengths, now become his downfall when he loses control and attempts to choke Sackrider in a fit of rage.

Security intervenes and arrests Jeremiah, signaling the apparent end of his reign over Tulsa’s underworld—for now. This shocking development leaves viewers wondering what the future holds, especially with the power vacuum that could ignite even fiercer conflicts moving forward.

### What’s Next for Tulsa King?

With Jeremiah behind bars and Dwight’s influence rising, Season 3 is poised for an intense power struggle in upcoming episodes. Fans will be eager to see how the shifting alliances and emerging threats shape the landscape of Tulsa’s crime world.

**To catch all the action from Tulsa King Season 3, Episode 7, stream the series exclusively on Paramount+.**

*Also recommended:*

– [7 Burning Questions Tulsa King Season 3 Must Answer](#)
– [Who is Bigfoot in Tulsa King Season 2? Everything You Need to Know](#)
– [Tulsa King Season 3 Cast and Characters: Meet the Stars Behind the Series](#)
– [Tulsa King Season 3 Episode 6 Ending Explained: Did Musso Orchestrate Bill’s Disappearance?](#)
https://www.sportskeeda.com/us/shows/tulsa-king-season-3-episode-7-ending-explained-what-happens-jeremiah

World Series prize money: How big is Dodgers’ payday vs. Blue Jays’ runner-up earnings?

The Los Angeles Dodgers successfully defended their World Series title with a thrilling 5-4 victory against the Toronto Blue Jays in a series-deciding Game 7 at Rogers Centre on Saturday. This win marks the Dodgers as the first team since the New York Yankees (1999-2000) to clinch consecutive World Series championships.

As Dodgers players celebrate their remarkable triumph, it’s worth exploring the financial rewards tied to their success in this year’s Fall Classic.

### MLB Postseason Prize Money Breakdown

Major League Baseball (MLB) divides playoff gate receipts among all postseason teams, with the World Series champions receiving the largest share. Last year, after defeating the New York Yankees, the Dodgers received 36 percent of the $129 million postseason pool, amounting to approximately $46.47 million.

From their share, Dodgers players earned around $477,440 each. For comparison, Yankees players earned roughly $354,571 each from their 24 percent share of the postseason pool.

According to Sportico, this year the Dodgers are expected to receive close to $500,000 per player in prize money, while the Blue Jays players could earn about $350,000 each. The total postseason pool is calculated based on gate receipts collected from playoff games, including:

– Two games in the Wild Card round
– Three games in the Division Series
– Four games in the League Championship Series
– Four games in the World Series

### Comparing MLB’s Prize Money to Other Leagues

When compared to other major sports leagues, MLB offers one of the most lucrative postseason prize pools. Last year, MLB had the second-highest distribution to players after the NBA.

– The reigning NBA champions, the Oklahoma City Thunder, awarded their players $828,000 each after their recent title run.
– The 2024 NFL Super Bowl champions, the Philadelphia Eagles, distributed $357,000 per player after their win over the Kansas City Chiefs.
– In the NHL, the Florida Panthers shared $250,000 per player following their third consecutive Stanley Cup victory.

The Dodgers’ continued excellence on the field is matched by significant financial rewards, highlighting the lucrative nature of championship success in professional sports.
https://www.sportskeeda.com/baseball/world-series-prize-money-how-big-dodgers-payday-vs-blue-jays-runner-up-earnings

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